Lysophosphatidic Acid Induced Apoptosis, DNA Damage, and Oxidative Stress in Spinal Cord Neurons by Upregulating LPA4/LPA6 Receptors

<div>LPA activates G<i>α</i>12/13–Rho–ROCK2 by upregulating LPA4 and LPA6. (a) Activation of the G<i>α</i>12/13 pathway is detected by the serum response factor response element (SRF-RE) luciferase reporter gene. (b, c) The expression of ROCK1 and ROCK2 in spinal cord neurons were measured by western blotting. 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Mediators of Inflammation

fig8

Figure 8

Figure 8: Lysophosphatidic Acid Induced Apoptosis, DNA Damage, and Oxidative Stress in Spinal Cord Neurons by Upregulating LPA4/LPA6 Receptors 