FAM171B as a Novel Biomarker Mediates Tissue Immune Microenvironment in Pulmonary Arterial Hypertension

<div>Visualizing the results of differential genes. (a) Clustering heat map of the genes exhibiting significantly differential expression PAH versus normal samples. Statistically significant DEGs were defined as |log2Foldchange| &gt; 0.5 and adjusted <svg height="8.68572pt" id="M7" style="vertical-align:-0.0498209pt" version="1.1" viewbox="-0.0498162 -8.6359 8.15071 8.68572" width="8.15071pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M600 480C600 590 528 650 384 650H143L137 622C222 614 225 607 210 531L130 127C113 41 106 36 23 28L17 0H294L300 28C204 36 195 42 212 127L243 284L314 263C327 263 339 263 352 264C465 271 600 337 600 480ZM508 481C508 351 402 304 329 304C289 304 265 311 250 317L295 559C302 594 310 606 323 611C335 616 350 619 367 619C455 619 508 573 508 481Z"></path></g></svg> value&lt;0.05. Cyan represents PAH samples; reddish-orange represents normal samples. (b) Volcano map of DEGs; red represents upregulated differential genes, black represents no significant difference in genes, and the green represents downregulated differential genes. DEGs: differentially expressed genes; PAH: pulmonary arterial hypertension.</div>

Mediators of Inflammation

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Figure 3

Figure 3: FAM171B as a Novel Biomarker Mediates Tissue Immune Microenvironment in Pulmonary Arterial Hypertension 