Inhibition of CEBPB Attenuates Lupus Nephritis via Regulating Pim-1 Signaling

<div>The knockdown of <i>CEBPB</i> inhibited the activation of NLRP3 inflammasomes in MRL/lpr mice. Relative expression of key proteins in the inflammasome-related signaling pathway in MRL/lpr mice after CEBPB downregulation (a); representative images of immunofluorescence detection of NLRP3 (b) and CEBPB (c) expression (50 <i>μ</i>m) in MRL/lpr mice with knockdown of <i>CEBPB</i>. (CEBPB, CCAAT/enhancer-binding protein <i>β</i>).</div>

Mediators of Inflammation

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Figure 4

Figure 4: Inhibition of CEBPB Attenuates Lupus Nephritis via Regulating Pim-1 Signaling 