Curcumin Targeting NF-κB/Ubiquitin-Proteasome-System Axis Ameliorates Muscle Atrophy in Triple-Negative Breast Cancer Cachexia Mice

Figure 3

Curcumin alleviates the weight and organ loss and improved malnutrition in tumor-bearing mice. (a) Body weight change curves of the three groups during the 4-week intervention period. (b) Statistical analysis of the terminal body weight of three groups of mice. (c) Statistical analysis of the food intake of the 3 groups of mice during the 4-week observation period. (d–g) Statistical analysis of serum total protein, albumin, cholesterol, and triglyceride of mice in the healthy group, the model group, and the curcumin group at the end of the experiment. (h) Statistical analysis of the weight of the main organs of the three groups of mice at the end of the experiment. /group. NS: not significant; , , , and by -test, compared to the model group. Data was shown as .

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