Research Article

Preliminary Report: Osteoarthritis and Rheumatoid Arthritis Synovial Fluid Increased Osteoclastogenesis In Vitro by Monocyte Differentiation Pathway Regulating Cytokines

Figure 5

Bone resorption in cultures with RA and healthy serum. Panel (a) shows the average resorbed bone volume measured with a laser microscope from the serum experiment. Panel (b) shows the average depth of the deepest pits on the bone slices. Panels (c) and (d) show examples of WGA-lectin-stained resorption pits (brown color) on the bone slices. 40x magnification. In image (c), there is a single TRAcP positive cell remaining attached to the bone after the mechanical removal of cells by brushing.
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