Preliminary Report: Osteoarthritis and Rheumatoid Arthritis Synovial Fluid Increased Osteoclastogenesis In Vitro by Monocyte Differentiation Pathway Regulating Cytokines

Figure 6

Bone resorption in cultures with RA and OA synovial fluid. Panel (a) shows the average resorbed bone volume measured with a laser microscope from the synovial fluid experiment. Example WGA-lectin stains of resorption pits on the bone slices from the cultures using RA and OA synovial fluids and healthy serum are shown in panels (c–e). 4x magnification. It was visually evident that the bone slices from the cultures with OA synovial fluid showed the most resorption.

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