Circulating MMP-12 as Potential Biomarker in Evaluating Disease Severity and Efficacy of Sublingual Immunotherapy in Allergic Rhinitis

Table 2

Association between and clinical variables in AR patients.

Variable	Serum MMP-12 level		Serum MRGPRX2 level
		value		value
Age	-0.088	0.924	0.012	0.884
BMI	-0.071	0.386	0.065	0.428
Baseline VAS	0.305	0.001	0.264	0.005
Baseline TNSS	0.309	0.001	0.016	0.870
Serum MRGPRX2 level	0.239	0.003	—	—
Serum MMP-12 level	—	—	0.239	0.003

AR: allergic rhinitis; BMI: body mass index; VAS: visual analogue scales; TNSS: total nasal symptoms score; MMP-12: matrix metalloproteinase-12; MRGPRX2: mas-related G protein-coupled receptor-X2.