Research Article

Postoperative Pulmonary Hemodynamics and Systemic Inflammatory Response in Pediatric Patients Undergoing Surgery for Congenital Heart Defects

Table 4

Baseline levels of inflammatory proteins.

Controls ()Patients () valueControls ()Patients () value

C5/C5a (upi)1392
(804-3756)
2442
(1027-3980)
0.209IL-13 (upi)509
(294-1090)
654
(311-1256)
0.492
CD40L (upi)4353
(2670-7079)
5233
(2871-7770)
0.677IL-16 (upi)521
(276-1116)
568
(262-1240)
0.749
G-CSF (upi)347
(198-603)
560
(245-867)
0.120IL-17 (upi)257
(146-450)
300
(190-556)
0.204
GM-CSF (upi)293
(146-356)
343
(168-492)
0.450IL-17E (upi)344
(183-565)
407
(224-786)
0.173
GROα (upi)1712
(1315-2578)
1770
(1204-2866)
0.824IL-27 (upi)221
(134-411)
304
(173-422)
0.401
I-309 (upi)636
(318-802)
674
(255-1210)
0.301IL-32α (upi)470
(220-980)
447
(257-990)
0.993
ICAM-1 (upi)38777
(30494-49330)
39756
(29716-48504)
0.847IP-10 (upi)646
(246-1185)
827
(432-1941)
0.052
IFN-γ (upi)269
(168-389)
329
(190-438)
0.434I-TAC (upi)522
(243-989)
706
(309-1024)
0.459
IL-1α (upi)363
(169-589)
423
(208-712)
0.407MCP-1 (upi)345
(261-637)
491
(238-876)
0.319
IL-1β (upi)191
(100-386)
185
(116-515)
0.766MIF (upi)6339
(5432-6838)
5677
(4635-7169)
0.444
IL-1RA (upi)1407
(759-2276)
1571
(605-2493)
0.903MIP-1α/β (upi)409
(232-580)
601
(249-914)
0.093
IL-2 (upi)268
(119-415)
324
(121-511)
0.378Serpin E1 (upi)44804
(40018-51686)
46656
(35898-61188)
0.670
IL-4 (upi)276
(179-444)
344
(208-510)
0.333RANTES (upi)58061
(47531-65624)
66140
(53982-76405)
0.012
IL-5 (upi)98
(56-198)
94
(76-226)
0.601SDF-1 (upi)3892
(3250-5036)
4251
(3323-5967)
0.419
IL-6 (upi)560
(260-983)
301
(192-718)
0.197TNF-α (upi)260
(144-473)
342
(151-629)
0.508
IL-8 (upi)202
(138-396)
282
(155-509)
0.272sTREM-1 (upi)264
(151-543)
381
(235-595)
0.312
IL-10 (upi)276
(132-399)
277
(197-490)
0.809IL-18 (upi)874
(500-1718)
951
(527-1602)
0.909
IL-12p70 (upi)243
(119-465)
261
(142-443)
0.612IL-21 (upi)401
(185-612)
379
(253-789)
0.512

Data are presented as median with interquartile range. Levels of inflammatory markers are given in units of pixel intensity (upi, chemiluminescence). Differences were analyzed using the general linear model after Box-Cox transformation of dependent variables.