Gut Microbiota: Target for Modulation of Gut-Liver-Adipose Tissue Axis in Ethanol-Induced Liver Disease

Table 1

Adipokine response to consumption of alcohol in rodents and humans.

Model	Effect of alcohol consumption	Reference
Rodent	Decrease in circulating adiponectin	[77]
	Decrease in adiponectin and cartonectin levels	[82, 86, 89, 109–112]
	Increase in leptin, resistin, IL-6, visfatin, chemerin, TNF-a, MCP-1, and RBP-4	[70, 83, 111, 113, 114]
	Decrease leptin	[88, 89]
	Unchanged leptin levels	[99]
	Increase resistin, chemerin, and visfatin	[102, 104, 106]
	Increase in triglyceride gradation and insulin resistance	[115, 116]
Human	Increase plasma adiponectin in chronic alcohol model	[117–119]
	Decrease plasma leptin in plasma chronic alcohol model	[97, 120, 121]
	Increase in leptin, resistin, and chemerin	[99, 103, 106]
	Unchanged leptin and resistin	[90–95, 103]
	Increase in adiponectin, resistin, ghrelin, TNF-alpha, and IL-6	[43, 48, 70, 78, 122–126]
	Decrease in acylation of stimulating protein	[127]
	Glucose intolerance	[97, 128, 129]