Research Article
WKYMVm/FPR2 Alleviates Spinal Cord Injury by Attenuating the Inflammatory Response of Microglia
Figure 1
WKYMVm had no effect on microglial proliferation or viability. (a) The molecular structure of WKYMVm. Cytotoxic effects of WKYMVm on HAPI microglia and primary microglia were examined by the CCK-8 assay. (b–d) HAPI microglia were incubated with increasing concentrations (0, 0.1, 1, 5, and 10 μmol/l) of WKYMVm for 12 h, 24 h, and 48 h at 37°C. (e–g) Primary microglia were incubated with increasing concentrations (0, 0.1, 0.5, 1, and 2 μmol/l) of WKYMVm for 12 h, 24 h, and 48 h at 37°C. M.Wt: molecular weight.
(a) |
(b) |
(c) |
(d) |
(e) |
(f) |
(g) |