Emodin Ameliorates Intestinal Dysfunction by Maintaining Intestinal Barrier Integrity and Modulating the Microbiota in Septic Mice

Figure 6

Emodin regulates intestinal community structure in septic mice. (a) Histogram of species distribution. The chart was the pie chart of the distribution of species at each level: including phyla, class, order, family, and genus. One color represented one specie; the length of the color block (histogram) or area of the color block (pie chart) presented the relative richness proportion of the species. Only species with top ten richness level were shown; the rest species were combined as others in the chart. (b) Alpha diversity of each treatment group. Use alpha diversity analysis to study the species diversity within a single sample. Ace, Chao1, Shannon, and Simpson indexes of each sample were statistically calculated at 97% similarity level. (c) Beta diversity of each treatment group. Beta diversity analysis was used to compare the differences of species diversity between different samples, using Bray-Curtis based PCoA and anosim analysis.

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