CpG Oligodeoxynucleotides Inhibit RANKL-Induced Osteoclast Formation by Upregulating A20 Deubiquitinase in RAW 264.7 Cells

<div>CpG-ODN induced A20 deubiquitinase. (a, b) A20 mRNA and protein expression were measured in RAW 264.7 cells incubated with CpG-ODN (1 <i>μ</i>M) for 0 to 4 days. (c, d) A20 mRNA expression in RAW 264.7 cells stimulated with either RANKL (100 ng/ml) or CpG-ODN (1 <i>μ</i>M) and both. 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Mediators of Inflammation

fig2

Figure 2

Figure 2: CpG Oligodeoxynucleotides Inhibit RANKL-Induced Osteoclast Formation by Upregulating A20 Deubiquitinase in RAW 264.7 Cells 