Topical Treatment of Colquhounia Root Relieves Skin Inflammation and Itch in Imiquimod-Induced Psoriasiform Dermatitis in Mice

Figure 3

CR treatment decreased immune cell infiltration and cytokine production in murine skins of IMQ-induced PsD. (a) Flow cytometry analysis of immune cells (CD45⁺ immune cells, neutrophils, macrophages, αβ T cells, and CD4⁺/CD8⁺αβ T cells) from skin tissues among groups. in the normal group, in the IMQ group, and in the IMQ+CR group. (b) mRNA expression of Il17a, Il22, and Ccl20 in mouse skin was measured via RT-qPCR, and the relative mRNA expression was normalized to Gapdh expression. in the normal group, in the IMQ group, and in the IMQ+CR group. Statistical analysis was performed using one-way ANOVA followed by post hoc Tukey’s test. Data are shown as the . .

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