Interleukin-10-Modified Adipose-Derived Mesenchymal Stem Cells Prevent Hypertrophic Scar Formation via Regulating the Biological Characteristics of Fibroblasts and Inflammation

Figure 5

IL-10-modified ADMSC underwent extensive apoptosis and survived for a short time after injection. (a) In the wound, the locally injected IL-10-ADMSC gradually reduced which was evaluated by observing green fluorescence, and representative tissue fluorescence image was displayed; (b) the GFP-labeled IL-10-ADMSC in the wound after different time of local injection of IL-10-ADMSC were statistically compared; (c–d) after different time of local injection of IL-10-ADMSC, Western blot was used to detect the expression of IL-10 in the wound. Representative protein bands were displayed and statistically compared protein band gray value. Scale bar: 10 μm. Data was expressed as (), and each analysis was repeated at least 3 times independently; value was calculated by Student’s test; ns was , was , was , and was vs. ADMSC group.

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