Interleukin-10-Modified Adipose-Derived Mesenchymal Stem Cells Prevent Hypertrophic Scar Formation via Regulating the Biological Characteristics of Fibroblasts and Inflammation

Figure 8

IL-10-modified ADMSC regulated wound inflammation. (a–d) After 3 days of treatment in different ways, we detected the expression of MCP-1, MIP-1β, IL-1β, and IL-6mRNA expression in wound by RT-qPCR. (e, f) After 3 days of treatment in different ways, we detected CD45 and CD3 positive cell in the wound using immunofluorescence (e, f). ; scale bar: 10 μm. Data was expressed as (); value was calculated by one-way ANOVA; was vs. ADMSC group; ns was , ^## was , and ^### was vs. control group.

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