Hepatoprotective Effect of Mitochondria-Targeted Antioxidant Mito-TEMPO against Lipopolysaccharide-Induced Liver Injury in Mouse

Figure 3

Mito-TEMPO alleviates oxidative stress in LPS-induced sepsis. (a) MDA and SOD activity in serum from LPS-induced sepsis mice. (b, c) Measurement of mitochondrial superoxide production in the liver from LPS-induced sepsis mice using a fluorescent MitoSOX probe (, 20 μm). (d) The protein expression levels of Sirt3, SOD2, and Ac-SOD2 in the liver were detected by western blot. per group. Data are presented as the from at least three independent experiments. , , , and .

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