Identification of Diagnostic Genes and Effective Drugs Associated with Osteoporosis Treatment by Single-Cell RNA-Seq Analysis and Network Pharmacology

<div>Identification of hub genes. (a) Volcano plot of differentially expressed genes between osteoporosis and nonosteoporosis. (b) Heatmap of differentially expressed genes between osteoporosis and nonosteoporosis. (c) Venn of differentially expressed genes and target genes for osteoporosis drugs. (d) CD45-BM-MSCs score differences analysis between osteoporosis and nonosteoporosis. (e) CD45+BM-MSCs score differences analysis between osteoporosis and nonosteoporosis. (f) The correlation analysis between 17 hub genes and CD45-BM-MSCs subpopulation or CD45+BM-MSCs subpopulation.</div>

Mediators of Inflammation

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Figure 2: Identification of Diagnostic Genes and Effective Drugs Associated with Osteoporosis Treatment by Single-Cell RNA-Seq Analysis and Network Pharmacology 

Figure 2 | Identification of Diagnostic Genes and Effective Drugs Associated with Osteoporosis Treatment by Single-Cell RNA-Seq Analysis and Network Pharmacology 