Research Article
Effect of Mean Platelet Volume to Platelet Count Ratio on Mortality in Peritoneal Dialysis
Table 1
Baseline characteristics of patients stratified by MPV/PC value.
| | Variables | MPV/PC | value | Total
() | <0.035
() | 0.035-0.045
() | 0.046-0.060
() | >0.060
() |
| | MPV/PC | | | | | | | | Age (years) | | | | | | <0.001 | | Male gender (%) | 873 (59.3%) | 204 (56.4%) | 228 (62.6%) | 239 (61.4%) | 202 (56.4%) | 0.176 | | BMI (kg/m2) | | | | | | <0.001 | | Primary disease | | | | | | <0.001 | | Glomerulonephritis (%) | 886 (60.1%) | 180 (49.7%) | 212 (58.2%) | 233 (59.9%) | 261 (72.9%) | | | Diabetic nephropathy (%) | 328 (22.3%) | 108 (29.8%) | 94 (25.8%) | 84 (21.6%) | 42 (11.7%) | | | Hypertensive nephropathy (%) | 107 (7.3%) | 32 (8.8%) | 27 (7.4%) | 28 (7.2%) | 20 (5.6%) | | | Others (%) | 152 (10.3%) | 42 (11.6%) | 31 (8.5%) | 44 (11.3%) | 35 (9.8%) | | | Hypertension (%) | 291 (19.8%) | 89 (24.6%) | 75 (20.6%) | 76 (19.5%) | 51 (14.2%) | 0.006 | | Diabetes (%) | 375 (25.5%) | 120 (33.1%) | 104 (28.6%) | 95 (24.4%) | 56 (15.6%) | <0.001 | | CVD (%) | 565 (38.4%) | 169 (46.8%) | 138 (37.9%) | 147 (37.8%) | 111 (31.1%) | <0.001 | | CCI | | | | | | <0.001 | | Hemoglobin (g/L) | | | | | | 0.006 | | Platelet (109/L) | | | | | | <0.001 | | MPV (fL) | | | | | | <0.001 | | Serum albumin (g/L) | | | | | | 0.392 | | Total cholesterol (mmol/L) | | | | | | <0.001 | | Triglyceride (mmol/L) | 1.36 (0.96-1.96) | 1.48 (1.01-2.28) | 1.42 (1.01-2.00) | 1.35 (0.98-2.06) | 1.28 (0.94-1.76) | < 0.001 | | Uric acid (μmol/L) | | | | | | 0.281 | | hs-CRP (mg/L) | 1.80 (0.70-6.14) | 3.02 (0.91-9.29) | 1.86 (0.66-5.78) | 1.55 (0.54-5.25) | 1.22 (0.55-3.75) | < 0.001 | | Urea nitrogen (mmol/L) | 16.6 (13.2-21.6) | 16.1 (12.5-20.8) | 16.6 (13.3-21.6) | 16.1 (12.8-20.3) | 16.6 (13.6-21.4) | 0.014 | | Creatinine (μmol/L) | 717 (571-928) | 676 (550-850) | 683 (562-895) | 727 (554-930) | 773 (614-958) | <0.001 | | RRF (mL/min/1.73 m2) | 3.21 (1.84-5.03) | 3.34 (1.91-5.51) | 3.38 (2.16-5.31) | 3.33 (2.05-5.06) | 2.70 (1.48-4.04) | <0.001 | | Total Kt/V | | | | | | 0.016 | | Antiplatelet drugs | 140 (9.5%) | 49 (13.5%) | 36 (9.9%) | 32 (8.2%) | 23 (6.4%) | 0.009 |
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MPV/PC: mean platelet volume to platelet count ratio; BMI: body mass index; CVD: cardiovascular disease; CCI: Charlson comorbidity index; MPV: mean platelet volume; hs-CRP: high sensitive C-reactive protein; RRF: residual renal function; Kt/V: urea clearance index.
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