Effect of Mean Platelet Volume to Platelet Count Ratio on Mortality in Peritoneal Dialysis
Table 3
The association of MPV/PC with all-cause and CV mortality in PD patients.
Model 1a
Model 2b
Model 3c
HR (95% CI)
value
HR (95% CI)
value
HR (95% CI)
value
All-cause mortality
Continuous MPV/PCd
0.91 (0.87-0.96)
<0.001
0.96 (0.91-1.00)
0.058
0.97 (0.92-1.02)
0.177
Quartile 1
1.0
1.0
1.0
Quartile 2
0.78 (0.60-1.02)
0.074
0.89 (0.68-1.17)
0.412
0.97 (0.73-1.28)
0.814
Quartile 3
0.76 (0.57-1.00)
0.050
0.73 (0.55-0.96)
0.026
0.76 (0.57-1.02)
0.063
Quartile 4
0.55 (0.40-0.74)
<0.001
0.76 (0.56-1.04)
0.085
0.86 (0.63-1.19)
0.366
for trend
0.002
0.109
0.256
CV mortality
Continuous MPV/PCd
0.90 (0.83-0.96)
0.002
0.94 (0.88-1.01)
0.085
0.96 (0.90-1.03)
0.277
Quartile 1
1.0
1.0
1.0
Quartile 2
0.68 (0.46-0.99)
0.044
0.78 (0.54-1.15)
0.210
0.90 (0.61-1.33)
0.591
Quartile 3
0.68 (0.46-1.00)
0.048
0.66 (0.45-0.97)
0.034
0.76 (0.51-1.13)
0.173
Quartile 4
0.47 (0.31-0.73)
0.001
0.68 (0.44-1.05)
0.083
0.83 (0.53-1.30)
0.412
for trend
0.006
0.128
0.571
MPV/PC: mean platelet volume to platelet count ratio; PD: peritoneal dialysis; CV: cardiovascular; HR: hazard ratio; CI: confidence interval. aUnadjusted model. bAdjusted for age, gender, and body mass index. cAdjusted for model 2 covariates and Charlson comorbidity index, hemoglobin, albumin, total cholesterol, triglycerides, high-sensitivity C-reactive protein, total Kt/V, residual renal function, and the use of antiplatelet drugs. dPer 0.01 higher MPV/PC.
