Effect of Mean Platelet Volume to Platelet Count Ratio on Mortality in Peritoneal Dialysis
Table 4
The association of MPV/PC with all-cause mortality stratified by age in PD patients.
Model 1a
Model 2b
Model 3c
HR (95% CI)
value
HR (95% CI)
value
HR (95% CI)
value
Interaction analysis ()d
for interaction < 0.001
for interaction < 0.001
for interaction = 0.009
()
Continuous MPV/PCe
0.92 (0.86-0.98)
0.010
0.93 (0.87-0.99)
0.021
0.94 (0.88-1.01)
0.071
Quartile 1
1.0
1.0
1.0
Quartile 2
0.79 (0.55-1.15)
0.218
0.80 (0.55-1.16)
0.236
0.88 (0.60-1.29)
0.521
Quartile 3
0.54 (0.35-0.83)
0.005
0.54 (0.35-0.84)
0.006
0.60 (0.38-0.94)
0.026
Quartile 4
0.51 (0.34-0.78)
0.002
0.55 (0.36-0.84)
0.005
0.62 (0.40-0.96)
0.032
for trend
0.003
0.008
0.052
()
Continuous MPV/PCe
0.96 (0.89-1.04)
0.331
0.97 (0.90-1.05)
0.418
1.01 (0.94-1.09)
0.742
Quartile 1
1.0
1.0
1.0
Quartile 2
0.93 (0.62-1.39)
0.718
0.95 (0.63-1.44)
0.821
1.18 (0.77-1.81)
0.450
Quartile 3
0.91 (0.63-1.31)
0.603
0.89 (0.61-1.29)
0.535
0.94 (0.64-1.40)
0.769
Quartile 4
0.91 (0.58-1.43)
0.681
0.94 (0.59-1.48)
0.775
1.37 (0.84-2.22)
0.208
for trend
0.955
0.942
0.422
MPV/PC: mean platelet volume to platelet count ratio; PD: peritoneal dialysis; CV: cardiovascular; HR: hazard ratio; CI: confidence interval. aUnadjusted model. bAdjusted for gender and body mass index. cAdjusted for model 2 covariates and Charlson comorbidity index, hemoglobin, albumin, total cholesterol, triglycerides, high-sensitivity C-reactive protein, total Kt/V, residual renal function, and the use of antiplatelet drugs. dContinuous .ePer 0.01 higher MPV/PC.
