CCL-2 and CXCL-8: Potential Prognostic Biomarkers of Acute Kidney Injury after a Bothrops atrox Snakebite

Table 2

Laboratory characterization of the groups (AKI^(-)) and (AKI⁽⁺⁾).

Laboratory variable	AKI^(-)	AKI^(+)	value
Fibrinogen level (mg/dL, median (IQR))	207.6 (203.3-207.6)	82.6 (81.5-89.6)	0.0006
Platelets (×10^3/mm^3, median (IQR))	229.0 (191.5-276.0)	226.0 (181.5-256.0)	0.7961
Leukocytes (×10^3/mm^3, median (IQR))	8.75 (7.7-9.1)	9.90 (6.5-13.8)	0.5350
Erythrocytes (×10^6/mm^3, median (IQR))	4.82 (4.7-5.1)	4.70 (4.3-5.2)	0.3890
Hemoglobin (g/dL, median (IQR))	14.45 (13.9-15.4)	14.82 (12.9-15.7)	0.7304
Creatine kinase (IU/L, median (IQR))	176.0 (106.0-242.0)	208.0 (117.5-458.5)	0.1735
Lactate dehydrogenase (IU/L, median (IQR))	300.9 (200.1-300.2)	448.0 (346.0-707.0)	0.0005
Urea (mg/dL, median (IQR))	32.0 (25.5-36.0)	35.0 (26.0-59.0)	0.1050
Creatinine (mg/dL, median (IQR))	1.00 (0.90-1.25)	1.40 (1.15-1.80)	0.0036

The results are expressed as median (IQR), and the statistical analysis was performed using the Mann–Whitney test followed by the test. Statistical significance was considered at in all cases. Reference values: fibrinogen: 200-400 mg/dL; platelets: 130-/mm³; leukocytes: 4-/mm³; hemoglobin: 13.0-16.0 g/dL for males and 12.0-14.0 g/dL for females; creatine kinase: 24-190 IU/L; lactate dehydrogenase: 211-423 IU/L; urea: 10-45 mg/dL; creatinine: 0.5-1.2 mg/dL.