Research Article

Study on the Anti-demyelination Mechanism of Bu-Shen-Yi-Sui Capsule in the Central Nervous System Based on Network Pharmacology and Experimental Verification

Figure 12

BSYS serum inhibits H2O2-induced apoptosis of OLN-93 cells via regulating Akt phosphorylation. (a, b) The apoptotic cells (red fluorescence) were detected by TUNEL, and the nuclei (blue fluorescence) were stained by DAPI. . (c)–(f) Representative blots and statistical graphs of relative protein expression of Bax, Bcl-2, and c-caspase3 in OLN-93 cells. Data are presented as , compared with the CON group, ####; compared with the H2O2 group, , , , ; and compared with the H2O2 + BSYS serum group, ▲▲, ▲▲▲, ▲▲▲▲.
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