Lipopolysaccharide Inhibits Autophagy and Promotes Inflammatory Responses via p38 MAPK-Induced Proteasomal Degradation of Atg13 in Hepatic Stellate Cells

<div>Increased serum LPS level is associated with poor prognosis of ACLF. Plasma from acute-on-chronic liver failure (ACLF) patients at admission and from cirrhotic patients were tested for LPS. (a) LPS level in ACLF patients was significantly increased compared to cirrhotic controls. 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Mediators of Inflammation

fig1

Figure 1

Figure 1: Lipopolysaccharide Inhibits Autophagy and Promotes Inflammatory Responses via p38 MAPK-Induced Proteasomal Degradation of Atg13 in Hepatic Stellate Cells 

Figure 1 | Lipopolysaccharide Inhibits Autophagy and Promotes Inflammatory Responses via p38 MAPK-Induced Proteasomal Degradation of Atg13 in Hepatic Stellate Cells 