The mir-21 Inhibition Enhanced HUVEC Cellular Viability during Hypoxia-Reoxygenation Injury by Regulating PDCD4

Table 2

Baseline features of the study participants.

Parameters	Healthy participants ()	Patients with single-vessel CAD ()	Patients with double-vessel CAD ()	Patients with multivessel CAD lesion ()
Age (years)					0.539	0.217	0.184
Male/female	28/28	35/21	52/40	76/63	0.492	0.113	0.086
Systolic BP (mmHg)					0.089	0.326	0.251
Diastolic BP (mmHg)					0.091	0.144	0.163
Heart rate (bpm)					0.257	0.389	0.446
Body mass index (kg/m^2)					0.428	0.507	0.453
Current tobacco smoking	52% (29)	56% (31)	60% (55)	58% (81)	0.642	0.715	0.783
Lipid disorders	—	86% (48)	88% (81)	92% (128)	—	—	—
Diabetes mellitus	—	28% (16)	32% (29)	34% (47)	—	—	—
Essential hypertension	—	57% (32)	66% (61)	68% (95)	—	—	—
LDL-C (mmol/L)					0.126	0.079	<0.001
TCHO (mmol/L)					0.078	0.092	<0.001
HDL-C (mmol/L)					0.099	0.086	<0.001
TG (mmol/L)					0.084	0.065	<0.001
Serum creatinine (mg/dL)					0.122	0.096	<0.001
Left ventricular ejection fraction					0.125	0.096	0.087
C-reactive protein (mg/L)					<0.001	<0.001	<0.001

: healthy controls versus single-vessel CAD groups; : healthy participants and dual-vessel lesion CAD subjects; : healthy volunteers and multivessel occluded CAD patients; TCHO: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol.