Abdominal Aortic Occlusion and the Inflammatory Effects in Heart and Brain

Figure 1

Schematic presentation of the experimental design. In this study, male C57BL/6 mice were used in this study. The mice were randomly divided into either sham group or AAO group. In the sham group, only a laparotomy was performed. In the AAO groups, the abdominal aorta under left renal 0.5 cm was occluded with sutures for 1–4 hr, followed by 24 hr of reperfusion. AAO, abdominal aorta occlusion; I/R, ischemia/reperfusion.