Abdominal Aortic Occlusion and the Inflammatory Effects in Heart and Brain

Figure 3

The effect of AAO on apoptosis of brain and heart in mice. The apoptotic cells of brain and heart slices were assessed by TUNEL staining. (a) Representative TUNEL-stained images of brain slices in MCAO model. (b) Quantification of TUNEL-positive cells at 24 hr after MCAO. (c) Representative TUNEL-stained images of hippocampus slices in AAO model. (d) Quantification of TUNEL-positive cells at 24 hr after AAO in brain. (e) Representative TUNEL-stained images of left ventricular slices in AAO model. (f) Quantification of TUNEL-positive cells at 24 hr after AAO in heart. Scale bar = 5 μm. Mean ± SD, n = 6. . TUNEL, terminal transferase-mediated dUTP nick-end labeling.

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