Review Article

TIRAP, TRAM, and Toll-Like Receptors: The Untold Story

Table 2

Reported SNPs in the TIRAP gene.

SNPAssociated diseasesReferences

S55NMeningeal tuberculosis[87]
D96NLymphoma[88]
E132KAtopic dermatitis[89]
S180LMalaria, sepsis, and Chagas cardiomyopathy[89ā€“91]
C539TTuberculosis susceptibility[92]

Abbreviations: C: cysteine; D: aspartate; E: glutamate; K: lysine; L: leucine; N: asparagine; S: serine; SNP: single-nucleotide polymorphism; T: threonine; TIRAP: Toll/interleukin-1 receptor domain-containing adaptor protein.