Comprehensive Analysis to Reveal Amino Acid Metabolism-Associated Genes as a Prognostic Index in Gastric Cancer

Figure 5

Four gene-based prognostic models were constructed using Lasso-Cox regression analysis. (a, b) The distribution of partial likelihood deviation of the Lasso coefficient preserves 4 variables when partial likelihood deviation reaches the minimum. (c) Alluvial diagram showing the connection between AAM clusters, gene clusters, and AAM score. (d) The level of the risk score in different AAM cluster subgroups. (e) The level of AAM score in different gene clusters. (f) The overall survival of AAM score. (g) ROC curves to predict the sensitivity and specificity of 1-, 3-, and 5-year survival according to the AAM score. (h, i) Ranked dot and scatter plots showing the AAM score distribution and patient survival status. (j) Heatmap showing four gene expression signatures in GC. (k, l) Establishment of nomogram and its performance verification.

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