Consensus Clustering and Survival-Related Genes of Cuproptosis in Cutaneous Melanoma

Figure 1

The genetic makeup of CRG variation in CM and its landscape. (a) The expression of 10 CRGs in normal skin tissues compared to that of CM tissues. Normal tissues are shown in blue, while malignant tissues are shown in red (). (b) The frequency of variations in the CRG copy number. A gain is denoted by the color red, whereas a loss is denoted by the color green. (c) Variation in the copy number of the CRG at various places on the chromosome. The color red indicates that the sample with the increased copy number is larger than the sample with the loss, and it is indicated by the color blue that the sample with the loss is larger than the increase. (d) A waterfall plot depicts the levels of CRG mutations. (e) Diagnostic and prognostic network for the CRGs. Red: “erasers”; orange: “readers”; gray: “writers”; CRG: cuproptosis-related gene; CM: cutaneous melanoma.

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