Low-Dose Taxol Promotes Neuronal Axons Extension and Functional Recovery after Spinal Cord Injury

Figure 4

(a)The spinal cord tissue of T8-T9 spinal cord transection injury model rat is obtained on 1th day after operation, and it shows an obvious gap in T8-T9 spinal cord tissue. HE-staining shows an obvious gap in T8-T9 spinal cord, indicating successfully injured. Scale: 1000 μm. (b) In vivo experiment diagram of low-dose Taxol can directly reflect the effect of low-dose Taxol on neuronal axon extension and limb motor functional recovery after SCI. The general idea of the diagram is that the addition of an appropriately low dose of Taxol combined with biomaterials could effectively increase the number of neurons and axonal extension, compared with no intervention group (with biomaterials), thus promoting the recovery of motor functions in rats after SCI.

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