Research Article

Association between the Systemic Immune-Inflammation Index and Thyroid Function in U.S. Adults

Table 2

Weighted univariate linear regression analysis between lnSII and thyroid function.

Thyroid functionlnSII
ContinuousCategorical
Tertile 1Tertile 2Tertile 3

β (95% CI), p-valueβ (95% CI), p-value
FT3−0.0603 (−0.1078, −0.0128)Reference−0.0242 (−0.0588, 0.0104)−0.0535 (−0.0851, −0.0218)
FT40.0072 (−0.0029, 0.0173)Reference−0.0053 (−0.0151, 0.0046)0.0068 (−0.0039, 0.0175)
TT3−0.0273 (−0.0559, 0.0013)Reference−0.0009 (−0.0349, 0.0332)−0.0325 (−0.0660, 0.0010)
TT40.1837 (0.0974, 0.2700) Reference0.0526 (−0.0504, 0.1555)0.2267 (0.1199, 0.3334)
TSH0.0108 (−0.0930, 0.1146)Reference0.0012 (−0.2306, 0.2330)0.0330 (−0.1330, 0.1989)
FT3/FT4−0.0918 (−0.1658, −0.0178)Reference−0.0078 (−0.0583, 0.0427)−0.0761 (−0.1349, −0.0172)
TG1.8916 (−0.0697, 3.8529)Reference0.1784 (−1.6907, 2.0476)3.6951 (0.6535, 6.7366)
TPOAb5.1330 (0.4263, 9.8398)Reference0.8370 (−6.0170, 7.6911)5.5685 (−1.4221, 12.5590)
TGAb−3.2196 (−8.6547, 2.2154)Reference0.7632 (−8.0861, 9.6124)−4.5393 (−10.4229, 1.3444)

Note: FT3, free triiodothyronine; FT4, free thyroxine; TT3, total triiodothyronine; TT4, total thyroxine; TSH, thyroid-stimulating hormone; TG, thyroglobulin; TGAb, thyroglobulin antibodies; and TPOAb, thyroid peroxidase antibodies. , , .