Association between the Systemic Immune-Inflammation Index and Thyroid Function in U.S. Adults
Table 5
Association between lnSII and thyroid function after subgroup analysis by BMI.
Outcomes
≤18.5 kg/m2
>18.5, ≤25.0 kg/m2
>25.0, ≤30.0 kg/m2
>30 kg/m2
p for interaction
β (95% CI), p-value
FT3
0.0243 (−0.1145, 0.1631)
−0.0277 (−0.0708, 0.0153)
−0.1536 (−0.1948, −0.1125)
−0.0417 (−0.0822, −0.0012)
<0.001
TT4
0.1705 (−0.2478, 0.5889)
0.1603 (0.0306, 0.2899)
0.1939 (0.0699, 0.3179)
0.0857 (−0.0364, 0.2078)
0.659
FT3/FT4
0.0235 (−0.2805, 0.3276)
−0.0554 (−0.1496, 0.0388)
−0.2245 (−0.3146, −0.1344)
−0.0588 (−0.1475, 0.0299)
0.021
TG
−1.1853 (−12.1406, 9.7699)
0.1532 (−3.2409, 3.5472)
−1.2561 (−4.5032, 1.9909)
5.1916 (1.9946, 8.3887)
0.031
Note: FT3, free triiodothyronine; FT4, free thyroxine; TT3, total triiodothyronine; TT4, total thyroxine; TG, thyroglobulin; and TGAb, thyroglobulin antibodies. , , . Bold values signify the statistically significant variables clearly distinguishable from those that are not.