Integrative Analysis of Transcriptome and Metabolome to Illuminate the Protective Effects of Didymin against Acute Hepatic Injury

Figure 3

Didymin alleviated oxidative damage and inflammatory response in LPS/D-Gal-induced ALI. (a–e) The activities of GSH-Rd, SOD, ROS, MDA, and iNOS were detected by commercially available kits. (f–h) The concentrations of IL-1β, TNF-α, and IL-6 were determined by enzyme-linked immunosorbent assay. (i) The mRNA expression level of TNF-α was detected by RT-PCR assays. (j) The expression of IL-6 was determined using western blot. Bands 1 to 6, respectively, represent the normal control group, didymin control group, model group, bifendate-treated group, and low- and high-dosages of didymin-treated groups. The data are presented as . ^# vs. the normal group; vs. the model group.

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