Integrative Analysis of Transcriptome and Metabolome to Illuminate the Protective Effects of Didymin against Acute Hepatic Injury

Figure 6

Didymin inhibited the PI3K/Akt pathway. (a–e) The expressions of p-PI3K, p-Akt, p-mTOR, P70S6K, and PTEN were determined by western blot. (f, g) The mRNA expression levels of PI3K and Akt were detected by RT-PCR assays. The bands 1 to 6, respectively, represent the normal control group, didymin control group, model group, bifendate-treated group, and low- and high-dosages of didymin-treated groups. The data are presented as .^# vs. the normal group; vs. the model group.

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