Integrative Analysis of Transcriptome and Metabolome to Illuminate the Protective Effects of Didymin against Acute Hepatic Injury

Figure 7

Didymin inhibited the TLR4/NF-κB pathway. (a) The immunohistochemical analysis of NF-κB (400x). (b–f) The expressions of TLR4, MyD88, NF-κB, p-IKKα/β/IKKα/β, and p-IκBα/IκBα were determined by western blot. (g) The mRNA level of NF-κB was detected by qPCR assays. The bands 1 to 6, respectively, represent the normal control group, didymin control group, model group, bifendate-treated group, and low- and high-dosages of didymin-treated groups. The data are presented as . ^# vs. the normal group; vs. the model group.

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