Urinary Modified C-Reactive Protein is Closely Associated with Tubulointerstitial Lesions in Lupus Nephritis

Figure 4

Immunohistochemistry staining of CRP in renal biopsies from patients with lupus nephritis and normal controls: (a(A)) CRP staining was positive in the tubules of patients with lupus nephritis (arrow). (a(B)) CRP staining was negative in patients with lupus nephritis. (a(C)) CRP staining was barely seen in the tubules of normal kidneys. (a(D)) Blank control (×400). Scale bars 100 μm; (b) the mean optical density of CRP in patients with lupus nephritis and normal controls; (c–f) the associations between the expression of CRP and pathologic indices; (g) associations between the expression of CRP and the levels of urinary mCRP; (h–j) comparisons of the expression of CRP between patients with tubulointerstitial lesions and patients without tubulointerstitial lesions. CRP, C reactive protein; LN, lupus nephritis.

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