Urinary Modified C-Reactive Protein is Closely Associated with Tubulointerstitial Lesions in Lupus Nephritis

Figure 6

CRP production and secretion by HK2 cells: (a) the levels of nCRP; (b) mCRP in the supernatant of HK2 cells treated with IgG from patients with lupus nephritis for 24–72 hr were significantly higher than those exposed to normal IgG; (c) the expression of CRP mRNA in HK2 cells stimulated with IgG from patients with lupus nephritis for 24–72 hr was significantly higher than that in HK2 cells exposed to normal IgG. The above experiments were repeated three times. nCRP, native C reactive protein; mCRP, modified C reactive protein; LN, lupus nephritis.

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