Improved Antitumor Effect of NK Cells Activated by Neutrophils in a Bone Marrow Transplant Model

Figure 2

Changes in the function of NK cells after BMT. The expression of CD107a, as a functional marker for the identification of NK cell activity, was detected by flow cytometry in each Ly49C/I⁺ and Ly49G2⁺ NK cells of recipient mice before BMT (day 0: donor, ) and on days 14 (), 21 (), 28 () and 56 () after BMT. The mean fluorescence intensity (MFI) is shown in number and triangle symbol in the upper right corner of each plot in the representative data (a). The activity of Ly49C/I⁺ NK cells (b) and Ly49G2⁺ NK cells (c) of recipient mice was determined as the MFI plus or minus standard deviation values of three independent experiments.

(a)

(b)

(c)