Improved Antitumor Effect of NK Cells Activated by Neutrophils in a Bone Marrow Transplant Model

Figure 3

Neutrophils enhance licensed NK cells after BMT. Intraperitoneal injection of PBS (), PB (), G-PB (5) was performed to ehnance licensed NK cell at day21 after BMT. The activation of licensed NK cells by neutrophils was measured using the MFI of CD107a of Ly49C/I⁺ NK cells (a) and Ly49G2⁺ NK cells (b) before intraperitoneal injection (day 0) and 2 days and 14 days after intraperitoneal injection. . G-PB: peripheral blood from rmG-CSF-treated mice; PB: peripheral blood from untreated B10 mice; PBS: phosphate-buffered saline.

(a)

(b)