The Dopamine D1 Receptor Attenuates Titanium Particle-Induced Inhibition of Osteogenesis by Activating the Wnt Signaling Pathway
Titanium particles inhibit D1R expression in vitro and ex vivo of human. (a) Representative images of western blots probed with antibodies against D1R, D2R, D3R, D4R, and D5R. (b–f) Quantification of D1R, D2R, D3R, D4R, and D5R protein levels. per group. NS: not statistically significant, and vs. the ctrl group at the same time point. (g) Representative images showing IHC staining of D1R in human synovial specimens. Scale bar: 50 μM.