Research Article

Fibrinogen Is Associated with Prognosis of Critically Ill Patients with Sepsis: A Study Based on Cox Regression and Propensity Score Matching

Table 2

Baseline characteristics of normal fibrinogen and low fibrinogen group before and after matching.

CharacteristicsBefore matchingAfter matching
Normal fibrinogen ()Low fibrinogen ()Normal fibrinogen ()Low fibrinogen ()

Gender, male, (%)783 (55.1)204 (54.5)0.89112 (46.9)127 (53.1)0.20
Age, mean (SD)63.62 (16.58)57.99 (15.13)<0.00160.12 (16.13)60.33 (16.11)0.89
AKI, (%)984 (69.2)311 (83.2)<0.001187 (78.2)192 (80.3)0.65
COPD, (%)97 (6.8)28 (7.5)0.7425 (10.5)20 (8.4)0.53
CKD, (%)307 (21.6)69 (18.4)0.2145 (18.8)48 (20.1)0.82
Acute respiratory failure, (%)778 (54.8)235 (62.8)0.01154 (64.4)145 (60.7)0.45
Liver cirrhosis, (%)292 (20.5)202 (54.0)<0.00198 (41.0)91 (38.1)0.58
AMI, (%)88 (6.2)20 (5.3)0.6319 (7.9)16 (6.7)0.73
HF, (%)434 (30.5)62 (16.6)<0.00153 (22.2)53 (22.2)1.00
Hypertension, (%)261 (18.4)59 (15.8)0.2836 (15.1)37 (15.5)1.00
Thrombosis, (%)207 (14.6)61 (16.3)0.4538 (15.9)48 (20.1)0.28
AF, (%)489 (34.4)80 (21.4)<0.00168 (28.5)65 (27.2)0.84
Cerebral infarction, n (%)60 (4.2)9 (2.4)0.147 (2.9)7 (2.9)1.00
Cerebral hemorrhage n (%)18 (1.3)4 (1.1)0.973 (1.3)1 (0.4)0.62
WBC, mean (SD)13.83 (11.49)12.74 (8.85)0.0914.63 (13.04)13.32 (9.58)0.21
Platelet, mean (SD)186.34 (123.92)112.18 (72.78)<0.001128.05 (77.83)131.74 (79.27)0.61
Creatine, mean (SD)2.89 (2.34)3.56 (2.28)<0.0013.25 (2.52)3.40 (2.20)0.48
Hemoglobin, mean (SD)10.89 (2.50)10.49 (2.71)0.0110.65 (2.50)10.73 (2.88)0.77
Albumin, mean (SD)2.93 (0.68)2.74 (0.72)<0.0012.78 (0.65)2.84 (0.74)0.32
Bilirubin, mean (SD)3.20 (6.45)7.80 (9.50)<0.0015.74 (9.11)5.20 (7.50)0.48
Lactate, mean (SD)3.40 (2.87)5.04 (4.26)<0.0014.06 (3.37)4.27 (3.47)0.49
Potassium, mean (SD)4.35 (1.01)4.44 (1.11)0.144.38 (1.08)4.30 (0.92)0.39
Sodium, mean (SD)136.70 (6.64)134.88 (7.44)<0.001135.81 (7.82)135.59 (7.39)0.76
PT, mean (SD)18.91 (11.04)25.68 (15.35)<0.00121.76 (13.62)21.73 (10.45)0.98
PTT, mean (SD)37.65 (19.34)48.21 (23.79)<0.00142.82 (23.96)42.93 (20.95)0.96
SOFA score, mean (SD)10.40 (4.70)13.90 (4.74)<0.00112.44 (4.22)12.74 (4.73)0.45
SAPS II score, mean (SD)48.11 (16.36)51.73 (17.22)<0.00151.13 (16.66)51.07 (17.78)0.97
Fibrinogen, mean (SD)272.95 (72.81)105.14 (29.54)<0.001255.28 (73.59)106.96 (28.35)<0.001
Inhospital death, (%)631 (44.4)231 (61.8)<0.001132 (55.2)134 (56.1)0.93