Fibrinogen Is Associated with Prognosis of Critically Ill Patients with Sepsis: A Study Based on Cox Regression and Propensity Score Matching

Table 3

Baseline characteristics of normal fibrinogen and elevated fibrinogen group before and after matching.

Characteristics	Before matching			After matching
	Normal fibrinogen ()	Elevated fibrinogen ()		Normal fibrinogen ()	Elevated fibrinogen ()
Gender, male, (%)	783 (55.1)	893 (56.9)	0.35	532 (55.1)	523 (54.2)	0.72
Age, mean (SD)	63.62 (16.58)	64.30 (16.32)	0.26	64.76 (17.19)	64.57 (16.68)	0.81
AKI, (%)	984 (69.2)	1060 (67.5)	0.33	635 (65.8)	645 (66.8)	0.67
COPD, (%)	97 (6.8)	114 (7.3)	0.70	70 (7.3)	67 (6.9)	0.86
CKD, (%)	307 (21.6)	376 (23.9)	0.14	219 (22.7)	217 (22.5)	0.96
Acute respiratory failure, (%)	778 (54.8)	791 (50.4)	0.019	508 (52.6)	498 (51.6)	0.68
Liver cirrhosis, (%)	292 (20.5)	68 (4.3)	<0.001	51 (5.3)	58 (6.0)	0.55
AMI, (%)	88 (6.2)	89 (5.7)	0.60	62 (6.4)	56 (5.8)	0.64
HF, (%)	434 (30.5)	494 (31.5)	0.61	319 (33.1)	310 (32.1)	0.70
Hypertension, (%)	261 (18.4)	361 (23.0)	0.002	202 (20.9)	199 (20.6)	0.91
Thrombosis, (%)	207 (14.6)	227 (14.5)	0.97	142 (14.7)	150 (15.5)	0.66
AF, (%)	489 (34.4)	552 (35.2)	0.70	341 (35.3)	345 (35.8)	0.89
Cerebral infarction, (%)	60 (4.2)	82 (5.2)	0.23	45 (4.7)	43 (4.5)	0.91
Cerebral hemorrhage, (%)	18 (1.3)	25 (1.6)	0.55	11 (1.1)	13 (1.3)	0.84
WBC, mean (SD)	13.83 (11.49)	15.10 (19.62)	0.033	13.77 (12.26)	13.85 (12.86)	0.89
Platelet, mean (SD)	186.34 (123.92)	222.54 (137.04)	<0.001	200.08 (124.85)	201.86 (127.13)	0.76
Creatine, mean (SD)	2.89 (2.34)	2.88 (2.48)	0.89	2.74 (2.30)	2.72 (2.22)	0.80
Hemoglobin, mean (SD)	10.89 (2.50)	11.05 (2.38)	0.083	11.12 (2.51)	11.01 (2.36)	0.32
Albumin, mean (SD)	2.93 (0.68)	2.91 (0.66)	0.43	2.94 (0.69)	2.95 (0.66)	0.83
Bilirubin, mean (SD)	3.20 (6.45)	1.57 (2.86)	<0.001	1.64 (3.08)	1.78 (3.25)	0.35
Lactate, mean (SD)	3.40 (2.87)	2.75 (2.03)	<0.001	2.95 (2.19)	2.84 (2.07)	0.26
Potassium, mean (SD)	4.35 (1.01)	4.34 (0.96)	0.78	4.32 (0.96)	4.31 (0.94)	0.76
Sodium, mean (SD)	136.70 (6.64)	137.12 (6.58)	0.083	137.25 (6.46)	137.29 (6.49)	0.90
PT, mean (SD)	18.91 (11.04)	18.99 (14.60)	0.88	18.05 (11.04)	18.26 (12.09)	0.69
PTT, mean (SD)	37.65 (19.34)	35.33 (17.59)	0.001	35.85 (17.46)	35.81 (18.62)	0.96
SOFA score, mean (SD)	10.40 (4.70)	8.89 (4.44)	<0.001	9.44 (4.45)	9.26 (4.45)	0.37
SAPSII score, mean (SD)	48.11 (16.36)	46.35 (16.81)	0.004	47.07 (16.15)	46.42 (16.28)	0.38
Fibrinogen, mean (SD)	272.95 (72.81)	612.33 (170.24)	<0.001	283.57 (70.67)	603.98 (166.37)	<0.001
Inhospital death, (%)	631 (44.4)	472 (30.1)	<0.001	387 (40.1)	310 (32.1)	<0.001