Jia-Wei-Kai-Xin-San Treatment Alleviated Mild Cognitive Impairment through Anti-Inflammatory and Antiapoptotic Mechanisms in SAMP8 Mice

Figure 8

JWKXS treatment prevented Aβ1–42 induced PC12 cells apoptosis. (a) Cell apoptosis analysis by flow cytometry. (b) Apoptotic rate (%) of early and late-stage apoptotic cells. (c–g) The protein expression levels of apoptotic factors Fas, cleaved-CASP8/CASP8, cleaved-PARP/PARP, cleaved-CASP3/CASP3, and Bax, Bcl2 and Bcl-xl. GAPDH and β-actin served as the internal control. Data are presented as mean ± SD. FITC: fluorescein isothiocyanate; PI: propidium iodide.

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