Key Cell Types and Biomarkers in Heart Failure Identified through Analysis of Single-Cell and Bulk RNA Sequencing Data

Figure 2

Overview of cell populations was profiled for healthy donors and those with failing hearts: (a) the UMAP plot of scRNA-seq data depicts 10 distinct cell types; (b) the UMAP plot of cells grouped by color for DCM, ICM, and normal groups; (c) the percentage of various types of cells in DCM, ICM, and normal groups; (d) dot plot of the average expression levels of canonical markers across cell-type clusters, where the dot size maps to marker expression ratio, and color gradient correspond to gene expression level from low (green) to high (red).

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