Key Cell Types and Biomarkers in Heart Failure Identified through Analysis of Single-Cell and Bulk RNA Sequencing Data

Figure 3

Differential expression analysis of myeloid cells: (a) volcano plot exhibiting the differentially expressed genes among myeloid cells in heart failure compared to the normal (left: DCM vs. normal; right: ICM vs. normal). Orange and green points indicated upregulated and downregulated genes, respectively; (b) Venn diagrams of intersections among genes significantly upregulated (left) and downregulated (right); (c, d) the enriched analysis for common upregulated DEGs (c) and common downregulated DEGs (d) via the Metascape online website. The pathways marked with red were those related with possible pathomechanism of heart failure.

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