Lymphocyte-to-C-Reactive Protein Ratio as an Early Sepsis Biomarker for Neonates with Suspected Sepsis

Table 3

Regression analysis to assess the presence of neonatal sepsis and severe sepsis according to LCR.

Variables	Univariate		Multivariate
	OR (95% CI)		OR (95% CI)
Presence of total sepsis
LCR	0.835 (0.805–0.867)	<0.001	0.861 (0.824–0.899)	<0.001
LCR group
Low LCR group	1		1
High LCR group	0.305 (0.239–0.389)	<0.001	0.389 (0.292–0.519)	<0.001
Presence of severe sepsis
LCR	0.883 (0.850–0.916)	<0.001	0.936 (0.898–0.975)	0.002
LCR group
Low LCR group	1		1
High LCR group	0.431 (0.340–0.547)	<0.001	0.601 (0.459–0.788)	<0.001

Notes: adjusted for age, temperature, heart rate, respiratory rate, body weight, PCT, total neutrophil count, AST, and ALT. Abbreviation: LCR: lymphocyte-to-C-reactive protein ratio.