The Long Noncoding RNA Gm9866/Nuclear Factor-<i>κ</i>B Axis Promotes Macrophage Polarization

<div>Long noncoding RNA Gm9866 is closely related to macrophage polarization. (a) LPS (lipopolysaccharide) reduced the expression levels of long noncoding RNA Gm9866. (b) IL4 (interleukin-4) increased the expression levels of long noncoding RNA Gm9866. (c) Real-time polymerase chain reaction analysis for the transfection efficiency of long noncoding RNA Gm9866. (d, e) Real-time polymerase chain reaction analysis showed that the mRNA expression of the M2-related genes MRC2 (macrophage mannose receptor 2) and MRC1 (macrophage mannose receptor 1) significantly increased after overexpression of long noncoding RNA Gm9866. (f) NF-<i>κ</i>B (nuclear factor-<i>κ</i>B) is a target of long noncoding RNA Gm9866. 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Mediators of Inflammation

fig2

Figure 2

Figure 2: The Long Noncoding RNA Gm9866/Nuclear Factor-<i>κ</i>B Axis Promotes Macrophage Polarization 

Mediators of Inflammation

The Long Noncoding RNA Gm9866/Nuclear Factor-κB Axis Promotes Macrophage Polarization

Figure 2