Mediators of Inflammation

Atherosclerosis in Rheumatoid Arthritis


Publishing date
02 Nov 2012
Status
Published
Submission deadline
15 Jun 2012

1Rheumatology Division, Marqués de Valdecilla University Hospital, IFIMAV, Santander, Spain

2Department of Rheumatology, Institute of Medicine, University of Debrecen Medical and Health Sciences Center, 98 Nagyerdei Street, 4032 Debrecen, Hungary

3Department of Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

4Department of Rheumatology, Charlotte Maxeke Johannesburg Academic Hospital, University of the Witwatersrand, Johannesburg, Johannesburg, South Africa


Atherosclerosis in Rheumatoid Arthritis

Description

Cardiovascular complications constitute the leading cause of death in patients with rheumatoid arthritis. Patients with this complex polygenic inflammatory rheumatic disease have metabolic abnormalities including a dyslipidemic pattern and insulin resistance. Surrogate markers of atherosclerosis have disclosed the presence of subclinical atherosclerosis in these patients. Besides genetic factors, chronic inflammation plays a pivotal role in the development of accelerated atherosclerosis in rheumatoid arthritis. Since the advent of biologic therapies for the management of rheumatoid arthritis, the incidence of cardiovascular complications seems to have decreased in patients with this disease. However, further studies are needed to shed light on the problem of augmented risk of cardiovascular disease in patients with rheumatoid arthritis.

Articles for this special issue on mechanisms associated with atherosclerosis in patients with rheumatoid arthritis are welcome. Potential topics include, but are not limited to:

  • Influence of genetic factors
  • Role of biomarkers of endothelial dysfunction
  • Influence of proinflammatory cytokines
  • The role of CRP as a marker of atherosclerosis
  • The presence of metabolic syndrome and insulin resistance
  • The influence of classic cardiovascular risk factors
  • The role of inflammation in the development of dyslipidemia
  • The implication of surrogate markers of atherosclerosis
  • The influence of biologic therapies, in particular TNF antagonist agents, on the modulation of endothelial dysfunction and cardiovascular risk of patients with rheumatoid arthritis

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/mi/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 489608
  • - Editorial

Atherosclerosis in Rheumatoid Arthritis

Miguel A. González-Gay | Zoltan Szekanecz | ... | Patrick Dessein
  • Special Issue
  • - Volume 2012
  • - Article ID 147354
  • - Review Article

Atherosclerosis and Rheumatoid Arthritis: More Than a Simple Association

Lorenzo Cavagna | Nicola Boffini | ... | Roberto Caporali
  • Special Issue
  • - Volume 2012
  • - Article ID 785946
  • - Review Article

Atherogenic Index and High-Density Lipoprotein Cholesterol as Cardiovascular Risk Determinants in Rheumatoid Arthritis: The Impact of Therapy with Biologicals

Calin D. Popa | Elke Arts | ... | Piet L. C. M. van Riel
  • Special Issue
  • - Volume 2012
  • - Article ID 714732
  • - Review Article

Atherosclerosis in Juvenile Idiopathic Arthritis

Ewa Jednacz | Lidia Rutkowska-Sak
  • Special Issue
  • - Volume 2012
  • - Article ID 347268
  • - Clinical Study

Serum Levels of Asymmetric Dimethylarginine and Apelin as Potential Markers of Vascular Endothelial Dysfunction in Early Rheumatoid Arthritis

Manuela Di Franco | Francesca Romana Spinelli | ... | Guido Valesini
  • Special Issue
  • - Volume 2012
  • - Article ID 574817
  • - Review Article

Genetic Markers of Cardiovascular Disease in Rheumatoid Arthritis

Luis Rodríguez-Rodríguez | Raquel López-Mejías | ... | Javier Martín
  • Special Issue
  • - Volume 2012
  • - Article ID 674265
  • - Clinical Study

Anti-TNF-Alpha-Adalimumab Therapy Is Associated with Persistent Improvement of Endothelial Function without Progression of Carotid Intima-Media Wall Thickness in Patients with Rheumatoid Arthritis Refractory to Conventional Therapy

Carlos Gonzalez-Juanatey | Tomas R. Vazquez-Rodriguez | ... | Miguel A. González-Gay
  • Special Issue
  • - Volume 2012
  • - Article ID 125458
  • - Review Article

Role of Adipokines in Atherosclerosis: Interferences with Cardiovascular Complications in Rheumatic Diseases

Morena Scotece | Javier Conde | ... | Oreste Gualillo
Mediators of Inflammation
 Journal metrics
Acceptance rate35%
Submission to final decision81 days
Acceptance to publication31 days
CiteScore3.570
Impact Factor3.545
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