Mediators of Inflammation

Inflammation and Cardiovascular Cross Talk in Ischemic Vascular Diseases


Status
Published

Lead Editor

1University of Ferrara, Ferrara, Italy

2Harvard Medical School, Boston, USA

3Curtin University, Perth, Australia


Inflammation and Cardiovascular Cross Talk in Ischemic Vascular Diseases

Description

Inflammation is a common mechanism involved in ischemic diseases such as peripheral, cardiac, and cerebral artery diseases. Looking for a paradigm of the involvement of inflammation in vascular ischemic events, myocardial infarction is the primary cause of death and hospitalization in developed countries. Even though the current standard therapy reduces acute myocardial infarction mortality, the long-term outcome of patients is not improved and they continue to face reinfarction events and/or anomalous left ventricular remodeling and heart failure. At the cardiac level, tissues show structural changes characterized by unrestrained digestion of extracellular matrix and excessive fibrosis in which the immune system and inflammation play a crucial role by interacting with the local damaged tissues through resident and recruited leukocytes. In particular, postmyocardial infarction repair is crucial to survival and recruited inflammatory cells remove debris and facilitate the repair process but, at the same time, exaggerated inflammation may also inhibit healing leading to adverse events.

Following a recent view, the different immune cell subsets involved act as messengers implicated in novel inflammatory networks that link different organ systems.

We invite authors to contribute to this special issue with original research and review articles aimed at understanding the meaning of specific cellular subsets or soluble factors involved either in the preliminary stages of the disease or in the reparative processes of ischemic vascular events. We also encourage submission of manuscripts on both basic studies and clinical studies.

Potential topics include but are not limited to the following:

  • Role of specific cell subsets and soluble mediators in myocardial/cerebral infarction
  • Mechanisms of stem-cells recruitment in cardiac reparative processes
  • Insights into ischemic events associated with other primary diseases including both type 1 and type 2 diabetes
  • Role of exosomes and noncoding small RNAs in mediating cell communication and recruitment in ischemic diseases
  • Translational and clinical studies aiming at evaluating the role of cytokine/chemokines and growth factors for the treatment of ischemic diseases

Articles

  • Special Issue
  • - Volume 2017
  • - Article ID 3161968
  • - Editorial

Inflammation and Cardiovascular Cross Talk in Ischemic Vascular Diseases

Giorgio Zauli | Veronica Tisato | ... | Mauro Vaccarezza
  • Special Issue
  • - Volume 2017
  • - Article ID 9327136
  • - Research Article

High Neutrophil-to-Lymphocyte Ratio Predicts Cardiovascular Mortality in Chronic Hemodialysis Patients

Han Li | Xiangxue Lu | ... | Shixiang Wang
  • Special Issue
  • - Volume 2017
  • - Article ID 7018393
  • - Review Article

Ischemia/Reperfusion Injury following Acute Myocardial Infarction: A Critical Issue for Clinicians and Forensic Pathologists

Margherita Neri | Irene Riezzo | ... | Emanuela Turillazzi
  • Special Issue
  • - Volume 2017
  • - Article ID 1382805
  • - Research Article

Amelioration of Inflammatory Cytokines Mix Stimulation: A Pretreatment of CD137 Signaling Study on VSMC

Wei Zhong | Bo Li | ... | Jin Chuan Yan
  • Special Issue
  • - Volume 2017
  • - Article ID 9257291
  • - Research Article

N-Acetylcysteine Attenuates Diabetic Myocardial Ischemia Reperfusion Injury through Inhibiting Excessive Autophagy

Sheng Wang | Chunyan Wang | ... | Zhongjun Zhang
  • Special Issue
  • - Volume 2017
  • - Article ID 1396398
  • - Review Article

Interleukin-6 “Trans-Signaling” and Ischemic Vascular Disease: The Important Role of Soluble gp130

Mario Luca Morieri | Angelina Passaro | Giovanni Zuliani
  • Special Issue
  • - Volume 2017
  • - Article ID 3795142
  • - Research Article

High Levels of Hemoglobin Promote Carotid Adventitial Vasa Vasorum Neoangiogenesis in Chronic Kidney Disease

Maria Vittoria Arcidiacono | Montserrat Martinez-Alonso | ... | Mercè Borràs
  • Special Issue
  • - Volume 2016
  • - Article ID 2182358
  • - Research Article

The Time Course of Markers of Neutrophil Extracellular Traps in Patients Undergoing Revascularisation for Acute Myocardial Infarction or Stable Angina Pectoris

Ragnhild Helseth | Svein Solheim | ... | Trine Baur Opstad
  • Special Issue
  • - Volume 2016
  • - Article ID 6529728
  • - Research Article

Dyslipidemia and Diabetes Increase the OPG/TRAIL Ratio in the Cardiovascular System

Barbara Toffoli | Bruno Fabris | ... | Stella Bernardi
Mediators of Inflammation
 Journal metrics
Acceptance rate36%
Submission to final decision53 days
Acceptance to publication29 days
CiteScore6.000
Impact Factor3.758
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