Mediators of Inflammation

Inflammation in the Disease: Mechanism and Therapies

Publishing date
03 May 2013
Submission deadline
14 Dec 2012

1Department of Internal Medicine, Faculty of Medical Sciences (FCM), State University of Campinas, Campinas, SP, Brazil

2Cancer Metabolism Research Group, Institute of Biomedical Sciences, University of São Paulo (USP), São Paulo, SP, Brazil

Inflammation in the Disease: Mechanism and Therapies


Inflammation in the face of harming stimuli protects the organism; therefore, it is a necessary process for survival, in which both innate and adaptive immunity may take part. Yet, it must be tightly controlled and terminated in order to warrant the reestablishment of body homeostasis. Therefore, the activation of resident inflammatory cells and the recruitment and modulation of migrating inflammatory cells must be ceased. When failure in neutralising acute inflammation occurs, there is risk for the development of chronic inflammation, which is the underlying feature shared by many chronic diseases.

We invite investigators to contribute original research articles as well as review articles that will stimulate the continuing efforts to understand the molecular pathology underlying chronic inflammation, the development of strategies to treat these conditions, and the evaluation of outcomes. We are particularly interested in articles describing the new modalities for clinical characterization of inflammatory process and measuring outcomes from treatment trials; advances in molecular genetics and molecular diagnostics; new insights into inflammation using animal models; current concepts in the treatment of this state using supplementation, exercise, SiRNA, stem cells, and gene therapy strategies. Potential topics include, but are not limited to:

  • Recent developments in inherited chronic inflammation disease research
  • Advances in genetics of inflammation
  • Role of inflammation in the metabolism
  • Resolution of inflammation

Before submission authors should carefully read over the journal's Author Guidelines, which are located at Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at according to the following timetable:

Mediators of Inflammation
 Journal metrics
Acceptance rate36%
Submission to final decision53 days
Acceptance to publication29 days
Impact Factor3.758

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